LARS1

Across TCGA patient cohorts, LARS1 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,286 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible LARS1-associated proteins across cancer lineages are NPM1, KDM3B, and DDX46. Each is linked with LARS1 in more than 7 cancer types. Because this analysis shows association rather than direction, both LARS1-to-partner and partner-to-LARS1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LARS1 versus NPM1 in GBM, with a Pearson correlation of 0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LARS1→partner) and Y-score (partner→LARS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	NPM1 →	+0.364	+0.380	<.001	<.001	3	8
OV	KDM3B →	+0.304	+0.659	.001	<.001	3	8
OV	DDX46 →	+0.259	+0.693	<.001	<.001	3	7
HNSC	GEMIN5 →	+0.260	+0.566	<.001	.001	2	8
HNSC	UIMC1 →	+0.331	+0.594	<.001	.001	3	6
GBM	TCERG1 →	+0.246	+0.239	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,286 associations by consensus.

LARS1 vs NPM1 — GBM

Explore this scatter interactively →