LARS1

Across TCGA patient cohorts, LARS1 protein abundance is significantly associated with the RNA expression of many other genes, with 20,981 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible LARS1-associated genes across cancer lineages are CARD8-AS1, MIR223HG, and FCGR2A. Each is linked with LARS1 in more than 6 cancer types. Because this analysis shows association rather than direction, both LARS1-to-partner and partner-to-LARS1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LARS1 versus CARD8-AS1 in UCEC, with a Pearson correlation of -0.32.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LARS1→partner) and Y-score (partner→LARS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CARD8-AS1 →	-0.543	-0.221	.004	.001	3	7
HNSC	MIR223HG →	-0.828	-0.189	<.001	.002	3	7
COAD	FCGR2A →	-0.939	-0.240	<.001	<.001	3	6
BRCA	CLEC1A →	-0.610	-0.262	<.001	<.001	3	6
COAD	FLI1 →	-0.658	-0.216	<.001	<.001	3	6
GBM	PRKCB →	-0.816	-0.206	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,981 associations by consensus.

LARS1 vs CARD8-AS1 — UCEC

Explore this scatter interactively →