LARP7

Across TCGA patient cohorts, LARP7 mutation is significantly associated with the RNA expression of many other genes, with 2,747 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LARP7-associated genes across cancer lineages are RNA5SP36, GAS2L1P1, and MTND2P23. Each is linked with LARP7 in more than 1 cancer types. Because this analysis shows association rather than direction, both LARP7-to-partner and partner-to-LARP7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP36 grouped by LARP7-low versus LARP7-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LARP7→partner) and Y-score (partner→LARP7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	RNA5SP36 →	+0.225	+4.704	<.001	.005	3	2
BLCA	GAS2L1P1 →	+0.089	+3.758	<.001	.008	3	2
BLCA	MTND2P23 →	+0.054	+4.859	<.001	.004	3	2
BLCA	RPS10P21 →	+0.302	+5.095	<.001	<.001	3	2
BLCA	USP9YP4 →	+0.068	+4.562	<.001	.006	3	2
BLCA	RNU7-14P →	+0.632	+4.112	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,747 associations by consensus.

RNA5SP36 by LARP7 expression — BLCA

Explore this box plot interactively →