LARP7

Across TCGA cell cohorts, LARP7 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,971 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible LARP7-associated GO terms across cancer lineages are Box C/D sno(s)RNA 3'-end processing, Box C/D sno(s)RNA metabolic process, and Box C/D sno(s)RNA processing. Each is linked with LARP7 in more than 18 cancer types. Because this analysis shows association rather than direction, both LARP7-to-partner and partner-to-LARP7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Box C/D sno(s)RNA 3'-end processing grouped by LARP7-low versus LARP7-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LARP7→partner) and Y-score (partner→LARP7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Box C/D sno(s)RNA 3'-end processing →	+0.194	+0.853	<.001	<.001	3	19
LUNG_SCLC	Box C/D sno(s)RNA metabolic process →	+0.194	+0.853	<.001	<.001	3	19
LUNG_SCLC	Box C/D sno(s)RNA processing →	+0.194	+0.853	<.001	<.001	3	19
UPPER_AERODIGESTIVE_TRACT	DNA-templated DNA replication →	+0.117	+0.760	.003	<.001	3	14
BLOOD_Lymphoma	DNA damage tolerance →	+0.070	+0.976	<.001	<.001	3	13
KIDNEY	U1 snRNA 3'-end processing →	+0.116	+0.489	.003	.006	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,971 associations by consensus.

Box C/D sno(s)RNA 3'-end processing by LARP7 expression — LUNG_SCLC

Explore this box plot interactively →