LARP4B

Across TCGA pan-cancer cohorts, LARP4B mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated LARP4B data layer compared with 22 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher LARP4B mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated LARP4B expression acts as an unfavorable survival marker, although some lineages such as UCEC and GBM show a favorable association.

UCEC, GBM, and LUAD are the cancer types where LARP4B mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Tertile	III,IV	1.000	0.314	.022	8	view →
GBM	DFS	Median	All	0.512	0.251	.005	7	view →
LUAD	OS	Median	II,III,IV	1.000	0.862	.004	6	view →
PDAC	OS	Tertile	IV	0.425	0.962	.024	6	view →
HNSC	OS	Median	IV	0.849	0.617	.020	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

LARP4B–UCEC (OS)

Open the UCEC breakdown →