LARP4

Across TCGA cell cohorts, LARP4 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,217 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible LARP4-associated GO terms across cancer lineages are Nuclear pore complex assembly, Nuclear transport, and DNA-templated DNA replication. Each is linked with LARP4 in more than 17 cancer types. Because this analysis shows association rather than direction, both LARP4-to-partner and partner-to-LARP4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nuclear pore complex assembly grouped by LARP4-low versus LARP4-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LARP4→partner) and Y-score (partner→LARP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Nuclear pore complex assembly →	+0.125	+0.943	.001	<.001	3	18
OESOPHAGUS	Nuclear transport →	+0.085	+0.868	<.001	.001	3	17
BONE	DNA-templated DNA replication →	+0.107	+0.474	<.001	<.001	3	17
LIVER	Endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	+0.144	+0.640	.009	.006	3	17
OESOPHAGUS	Nucleocytoplasmic transport →	+0.086	+0.868	<.001	.001	3	17
LIVER	rRNA 5'-end processing →	+0.144	+0.640	.009	.006	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,217 associations by consensus.

Nuclear pore complex assembly by LARP4 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →