LARP4

Across TCGA cell cohorts, LARP4 mutation is significantly associated with the RNA expression of many other genes, with 18 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible LARP4-associated genes across cancer lineages are C18orf63, ENPP6, and NTSR2. Each is linked with LARP4 in more than 1 cancer types. Because this analysis shows association rather than direction, both LARP4-to-partner and partner-to-LARP4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C18orf63 grouped by LARP4-low versus LARP4-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LARP4→partner) and Y-score (partner→LARP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	C18orf63 →	+0.012	+4.867	<.001	.009	3	1
LARGE_INTESTINE	ENPP6 →	+0.046	+3.793	<.001	.007	3	1
LARGE_INTESTINE	NTSR2 →	+0.082	+3.793	<.001	.007	3	1
STOMACH	OR7G2 →	+0.100	+5.285	<.001	.003	3	1
BLOOD_Leukemia	LRIT1 →	+0.030	+3.684	<.001	.004	3	1
BLOOD_Leukemia	RGR →	+0.029	+3.684	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 18 associations by consensus.

C18orf63 by LARP4 expression — BLOOD_Lymphoma

Explore this box plot interactively →