LARP1BP2

Across TCGA pan-cancer cohorts, LARP1BP2 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of LARP1BP2’s most consistent transcriptional readouts.

The strongest signal is observed in esophageal carcinoma (ESCA), where LARP1BP2 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LARP1BP2 is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.

ESCA, LUAD, and THCA are the cancer types where LARP1BP2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LARP1BP2 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
ESCA	All	II,III,IV	+0.210	.019	3	view →
LUAD	Female	All	+0.042	.048	1	view →
THCA	Female	All	−0.023	.031	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

LARP1BP2–ESCA

Open the ESCA breakdown →