LAPTM5

Across TCGA patient cohorts, LAPTM5 RNA expression is significantly associated with the protein abundance of many other proteins, with 24,433 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible LAPTM5-associated proteins across cancer lineages are PTPN6, PTPN7, and RASAL3. Each is linked with LAPTM5 in more than 9 cancer types. Because this analysis shows association rather than direction, both LAPTM5-to-partner and partner-to-LAPTM5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LAPTM5 versus PTPN6 in GBM, with a Pearson correlation of 0.87.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LAPTM5→partner) and Y-score (partner→LAPTM5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PTPN6 →	+0.817	+1.277	<.001	<.001	3	10
UCEC	PTPN7 →	+0.566	+1.344	<.001	<.001	3	10
GBM	RASAL3 →	+0.557	+1.320	<.001	<.001	3	10
GBM	MYO1F →	+0.865	+1.368	<.001	<.001	3	10
UCEC	NCF1 →	+0.829	+1.526	<.001	<.001	3	10
OV	ARHGAP25 →	+1.166	+2.050	.002	.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 24,433 associations by consensus.

LAPTM5 vs PTPN6 — GBM

Explore this scatter interactively →