LAPTM5

Across TCGA patient cohorts, LAPTM5 protein abundance is significantly associated with the RNA expression of many other genes, with 9,495 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible LAPTM5-associated genes across cancer lineages are HK3, CCR1, and BIN2. Each is linked with LAPTM5 in more than 5 cancer types. Because this analysis shows association rather than direction, both LAPTM5-to-partner and partner-to-LAPTM5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LAPTM5 versus HK3 in BRCA, with a Pearson correlation of 0.51.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LAPTM5→partner) and Y-score (partner→LAPTM5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	HK3 →	+1.291	+0.639	.001	.003	3	6
CCRCC	CCR1 →	+1.401	+0.503	.001	.006	3	6
CCRCC	BIN2 →	+1.108	+0.503	<.001	.006	3	5
CCRCC	PLEK →	+1.413	+0.511	.001	.005	3	5
OV	SASH3 →	+1.745	+0.595	<.001	.001	3	5
COAD	SIGLEC9 →	+1.017	+0.517	.003	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,495 associations by consensus.

LAPTM5 vs HK3 — BRCA

Explore this scatter interactively →