LAPTM5

Across TCGA patient cohorts, LAPTM5 mutation is significantly associated with the RNA expression of many other genes, with 284 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LAPTM5-associated genes across cancer lineages are RN7SL496P, RNU6-302P, and KRTAP22-2. Each is linked with LAPTM5 in more than 1 cancer types. Because this analysis shows association rather than direction, both LAPTM5-to-partner and partner-to-LAPTM5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL496P grouped by LAPTM5-low versus LAPTM5-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LAPTM5→partner) and Y-score (partner→LAPTM5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RN7SL496P →	+0.107	+4.282	<.001	.009	3	2
SKCM	RNU6-302P →	+0.472	+3.838	<.001	.006	3	2
LUSC	KRTAP22-2 →	+0.225	+5.578	<.001	.002	3	2
BLCA	CYP3A54P →	+0.413	+7.640	<.001	.009	3	1
SKCM	SLC25A5P4 →	+0.055	+3.661	<.001	.009	3	1
SKCM	EI24P4 →	+0.061	+4.254	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 284 associations by consensus.

RN7SL496P by LAPTM5 expression — SKCM

Explore this box plot interactively →