LAPTM4BP1

Across TCGA patient cohorts, LAPTM4BP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,440 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LAPTM4BP1-associated GO terms across cancer lineages are Response to ionizing radiation, Regulation of ubiquitin-dependent protein catabolic process, and Mitotic G2/M transition checkpoint. Each is linked with LAPTM4BP1 in more than 15 cancer types. Because this analysis shows association rather than direction, both LAPTM4BP1-to-partner and partner-to-LAPTM4BP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to ionizing radiation grouped by LAPTM4BP1-low versus LAPTM4BP1-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LAPTM4BP1→partner) and Y-score (partner→LAPTM4BP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Response to ionizing radiation →	+0.041	+0.160	<.001	<.001	3	15
STAD	Regulation of ubiquitin-dependent protein catabolic process →	+0.040	+0.126	<.001	<.001	3	15
LAML	Mitotic G2/M transition checkpoint →	+0.051	+0.293	<.001	<.001	3	15
STAD	Positive regulation of protein catabolic process →	+0.040	+0.129	<.001	<.001	3	15
STAD	Cellular response to ionizing radiation →	+0.045	+0.142	<.001	<.001	3	15
STAD	Maintenance of cell number →	+0.052	+0.194	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,440 associations by consensus.

Response to ionizing radiation by LAPTM4BP1 expression — STAD

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