LANCL3

Across TCGA patient cohorts, LANCL3 protein abundance is significantly associated with the RNA expression of many other genes, with 784 significant associations in total. GBM shows the largest number of these associations.

The most reproducible LANCL3-associated genes across cancer lineages are SRPX, N4BP2L1, and GPIHBP1. Each is linked with LANCL3 in more than 1 cancer types. Because this analysis shows association rather than direction, both LANCL3-to-partner and partner-to-LANCL3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LANCL3 versus SRPX in GBM, with a Pearson correlation of 0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LANCL3→partner) and Y-score (partner→LANCL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SRPX →	+1.476	+0.936	<.001	.001	3	2
GBM	N4BP2L1 →	+0.812	+1.033	<.001	.003	3	2
LUAD	GPIHBP1 →	+1.270	+0.743	<.001	<.001	3	2
GBM	ELOVL1 →	+0.487	+0.928	.002	.001	3	2
LUAD	SNPH →	-0.947	-0.698	<.001	<.001	3	1
LUAD	RHOXF1 →	+0.711	+0.472	.004	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 784 associations by consensus.

LANCL3 vs SRPX — GBM

Explore this scatter interactively →