LANCL3

Across TCGA cell cohorts, LANCL3 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,578 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible LANCL3-associated GO terms across cancer lineages are Cell-substrate junction organization, Positive regulation of post-translational protein modification, and Viral gene expression. Each is linked with LANCL3 in more than 7 cancer types. Because this analysis shows association rather than direction, both LANCL3-to-partner and partner-to-LANCL3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cell-substrate junction organization grouped by LANCL3-low versus LANCL3-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LANCL3→partner) and Y-score (partner→LANCL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Cell-substrate junction organization →	+0.208	+0.353	<.001	<.001	3	8
BREAST	Positive regulation of post-translational protein modification →	+0.064	+0.362	<.001	.008	3	8
BREAST	Viral gene expression →	+0.128	+0.451	<.001	<.001	3	8
BLOOD_Leukemia	Positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target →	+0.652	+0.818	<.001	<.001	3	8
BLOOD_Leukemia	Multivesicular body organization →	+0.067	+0.463	<.001	<.001	3	8
PANCREAS	Peptide modification →	-0.150	-0.605	<.001	.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,578 associations by consensus.

Cell-substrate junction organization by LANCL3 expression — BREAST

Explore this box plot interactively →