LANCL2

Across TCGA cell cohorts, LANCL2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,364 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible LANCL2-associated GO terms across cancer lineages are Peptide modification, U2-type prespliceosome assembly, and Regulation of protein localization to nucleus. Each is linked with LANCL2 in more than 11 cancer types. Because this analysis shows association rather than direction, both LANCL2-to-partner and partner-to-LANCL2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Peptide modification grouped by LANCL2-low versus LANCL2-high in CNS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LANCL2→partner) and Y-score (partner→LANCL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	Peptide modification →	+0.171	+0.682	<.001	<.001	3	12
BLOOD_Myeloma	U2-type prespliceosome assembly →	+0.088	+1.115	.002	.001	3	10
SOFT_TISSUE	Regulation of protein localization to nucleus →	+0.063	+0.806	.001	.002	3	10
PANCREAS	Latent virus replication →	+0.105	+0.735	<.001	<.001	3	9
PANCREAS	Release from viral latency →	+0.105	+0.735	<.001	<.001	3	9
UPPER_AERODIGESTIVE_TRACT	DNA-templated transcription initiation →	+0.090	+1.220	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,364 associations by consensus.

Peptide modification by LANCL2 expression — CNS

Explore this box plot interactively →