LANCL1

Across TCGA patient cohorts, LANCL1 RNA expression is significantly associated with the protein abundance of many other proteins, with 19,222 significant associations in total. GBM shows the largest number of these associations.

The most reproducible LANCL1-associated proteins across cancer lineages are SEC24A, ABI2, and TSN. Each is linked with LANCL1 in more than 5 cancer types. Because this analysis shows association rather than direction, both LANCL1-to-partner and partner-to-LANCL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LANCL1 versus SEC24A in GBM, with a Pearson correlation of -0.48.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LANCL1→partner) and Y-score (partner→LANCL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SEC24A →	-0.301	-0.844	<.001	<.001	3	6
PDAC	ABI2 →	+0.397	+0.453	<.001	<.001	3	6
LSCC	TSN →	+0.334	+0.542	.002	<.001	3	5
LSCC	SMARCAL1 →	+0.244	+0.635	<.001	<.001	3	5
LSCC	XRCC6 →	+0.212	+0.399	<.001	<.001	3	4
BRCA	RCOR3 →	+0.358	+0.444	<.001	.006	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,222 associations by consensus.

LANCL1 vs SEC24A — GBM

Explore this scatter interactively →