LANCL1

Across TCGA cell cohorts, LANCL1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,215 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible LANCL1-associated GO terms across cancer lineages are 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate metabolic process, Protein localization to cilium, and Microtubule-based transport. Each is linked with LANCL1 in more than 14 cancer types. Because this analysis shows association rather than direction, both LANCL1-to-partner and partner-to-LANCL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate metabolic process grouped by LANCL1-low versus LANCL1-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LANCL1→partner) and Y-score (partner→LANCL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate metabolic process →	+0.157	+1.624	.001	<.001	3	15
STOMACH	Protein localization to cilium →	+0.063	+1.301	<.001	.001	3	14
LUNG_NSCLC_LUSC	Microtubule-based transport →	+0.058	+1.670	<.001	.002	3	14
LUNG_SCLC	Transport along microtubule →	+0.078	+0.757	<.001	<.001	3	13
OVARY	Regulation of smoothened signaling pathway →	+0.041	+1.005	.001	<.001	2	14
LUNG_NSCLC_LUSC	Intraciliary anterograde transport →	+0.119	+1.868	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,215 associations by consensus.

1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate metabolic process by LANCL1 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →