LAMTOR5

Across TCGA patient cohorts, LAMTOR5 protein abundance is significantly associated with the RNA expression of many other genes, with 10,878 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible LAMTOR5-associated genes across cancer lineages are FOLR1, LAMTOR1, and GMNN. Each is linked with LAMTOR5 in more than 4 cancer types. Because this analysis shows association rather than direction, both LAMTOR5-to-partner and partner-to-LAMTOR5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LAMTOR5 versus FOLR1 in LSCC, with a Pearson correlation of 0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LAMTOR5→partner) and Y-score (partner→LAMTOR5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	FOLR1 →	+1.566	+0.217	<.001	<.001	3	5
BRCA	LAMTOR1 →	+0.474	+0.243	<.001	<.001	3	5
HNSC	GMNN →	-0.600	-0.261	<.001	.002	3	5
LUAD	TTK →	-0.978	-0.206	<.001	<.001	3	5
LUAD	BUB1 →	-0.832	-0.192	<.001	.003	3	5
HNSC	EXO1 →	-0.830	-0.261	.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,878 associations by consensus.

LAMTOR5 vs FOLR1 — LSCC

Explore this scatter interactively →