Across TCGA pan-cancer cohorts, LAMTOR4 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated LAMTOR4 data layer compared with 26 for mass-spec protein.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher LAMTOR4 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated LAMTOR4 expression acts as an unfavorable survival marker, although some lineages such as OV and LSCC show a favorable association.

LUAD, OV, and GBM are the cancer types where LAMTOR4 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Quartile	All	0.827	0.973	.011	20	view →
OV	DFS	Tertile	All	0.965	0.634	.015	16	view →
GBM	OS	Tertile	All	0.729	0.879	.008	14	view →
LSCC	OS	Median	III,IV	0.996	0.712	.024	3	view →
HNSC	DFS	Median	III,IV	0.919	1.000	.037	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

Exploration

Same gene, other analysis: LAMTOR4 tumor-vs-normal RNA expression · all LAMTOR4 data types