LAMTOR3

Across TCGA patient cohorts, LAMTOR3 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,764 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible LAMTOR3-associated proteins across cancer lineages are SPCS3, METAP1, and ARFIP1. Each is linked with LAMTOR3 in more than 4 cancer types. Because this analysis shows association rather than direction, both LAMTOR3-to-partner and partner-to-LAMTOR3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LAMTOR3 versus SPCS3 in BRCA, with a Pearson correlation of -0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LAMTOR3→partner) and Y-score (partner→LAMTOR3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SPCS3 →	-0.640	-0.537	<.001	<.001	3	5
OV	METAP1 →	+0.368	+0.608	<.001	<.001	3	5
UCEC	ARFIP1 →	+0.383	+0.688	.001	.001	3	5
OV	SEC24B →	+0.175	+0.398	<.001	.001	3	5
LUAD	FKBP11 →	-0.587	-0.379	<.001	<.001	3	5
LUAD	PLEKHA6 →	+0.655	+0.428	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,764 associations by consensus.

LAMTOR3 vs SPCS3 — BRCA

Explore this scatter interactively →