LAMTOR3

Across TCGA patient cohorts, LAMTOR3 protein abundance is significantly associated with the RNA expression of many other genes, with 10,260 significant associations in total. GBM shows the largest number of these associations.

The most reproducible LAMTOR3-associated genes across cancer lineages are MR1, SPAG5, and GPX1. Each is linked with LAMTOR3 in more than 5 cancer types. Because this analysis shows association rather than direction, both LAMTOR3-to-partner and partner-to-LAMTOR3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LAMTOR3 versus MR1 in LSCC, with a Pearson correlation of 0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LAMTOR3→partner) and Y-score (partner→LAMTOR3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	MR1 →	+0.767	+0.269	<.001	<.001	3	6
HNSC	SPAG5 →	-0.885	-0.210	.001	<.001	3	5
UCEC	GPX1 →	+1.421	+0.162	<.001	.002	3	5
LSCC	ADGRE4P →	+0.938	+0.290	<.001	<.001	3	5
HNSC	CENPF →	-1.118	-0.271	<.001	<.001	3	4
BRCA	CDC6 →	-0.957	-0.278	.001	.007	2	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,260 associations by consensus.

LAMTOR3 vs MR1 — LSCC

Explore this scatter interactively →