LAMTOR3

Across TCGA cell cohorts, LAMTOR3 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,893 significant associations in total. PANCREAS shows the largest number of these associations.

The most reproducible LAMTOR3-associated GO terms across cancer lineages are Golgi lumen acidification, Response to staurosporine, and Cellular response to staurosporine. Each is linked with LAMTOR3 in more than 14 cancer types. Because this analysis shows association rather than direction, both LAMTOR3-to-partner and partner-to-LAMTOR3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Golgi lumen acidification grouped by LAMTOR3-low versus LAMTOR3-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LAMTOR3→partner) and Y-score (partner→LAMTOR3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Golgi lumen acidification →	+0.104	+0.722	.001	.005	3	15
SOFT_TISSUE	Response to staurosporine →	+0.198	+0.888	<.001	<.001	3	13
SOFT_TISSUE	Cellular response to staurosporine →	+0.198	+0.888	<.001	<.001	3	13
LUNG_SCLC	Vesicle coating →	+0.101	+0.575	<.001	.005	3	12
URINARY_TRACT	Endosomal lumen acidification →	+0.120	+0.825	<.001	.001	3	11
CNS	Forebrain radial glial cell differentiation →	+0.135	+0.625	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,893 associations by consensus.

Golgi lumen acidification by LAMTOR3 expression — URINARY_TRACT

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