LAMTOR2

Across TCGA cell cohorts, LAMTOR2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,313 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible LAMTOR2-associated GO terms across cancer lineages are RISC complex assembly, Geranyl diphosphate metabolic process, and Regulation of lysosome size. Each is linked with LAMTOR2 in more than 8 cancer types. Because this analysis shows association rather than direction, both LAMTOR2-to-partner and partner-to-LAMTOR2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RISC complex assembly grouped by LAMTOR2-low versus LAMTOR2-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LAMTOR2→partner) and Y-score (partner→LAMTOR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	RISC complex assembly →	-0.084	-0.533	.001	.003	3	9
BREAST	Geranyl diphosphate metabolic process →	+0.129	+0.908	<.001	<.001	3	9
KIDNEY	Regulation of lysosome size →	+0.086	+0.472	.009	<.001	3	8
BLOOD_Myeloma	Threonyl-tRNA aminoacylation →	+0.131	+1.133	<.001	<.001	3	8
URINARY_TRACT	Positive regulation of dopamine receptor signaling pathway →	-0.181	-0.694	.003	.002	3	8
BREAST	Protein repair →	+0.184	+0.897	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,313 associations by consensus.

RISC complex assembly by LAMTOR2 expression — SOFT_TISSUE

Explore this box plot interactively →