LAMTOR1

Across TCGA patient cohorts, LAMTOR1 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,961 significant associations in total. GBM shows the largest number of these associations.

The most reproducible LAMTOR1-associated proteins across cancer lineages are INPPL1, LAMTOR5, and NADSYN1. Each is linked with LAMTOR1 in more than 7 cancer types. Because this analysis shows association rather than direction, both LAMTOR1-to-partner and partner-to-LAMTOR1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LAMTOR1 versus INPPL1 in BRCA, with a Pearson correlation of 0.56.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LAMTOR1→partner) and Y-score (partner→LAMTOR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	INPPL1 →	+0.400	+0.530	<.001	<.001	3	8
CCRCC	LAMTOR5 →	+0.252	+0.265	<.001	<.001	3	5
HNSC	NADSYN1 →	+0.592	+0.870	<.001	<.001	3	4
HNSC	PPME1 →	+0.392	+0.748	.001	.001	3	4
HNSC	NUMA1 →	+0.361	+0.618	<.001	<.001	3	4
OV	LAMTOR1_S98 →	+0.961	+0.783	<.001	.008	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,961 associations by consensus.

LAMTOR1 vs INPPL1 — BRCA

Explore this scatter interactively →