LAMTOR1

Across TCGA patient cohorts, LAMTOR1 protein abundance is significantly associated with the RNA expression of many other genes, with 6,301 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible LAMTOR1-associated genes across cancer lineages are C18orf54, TMEM41B, and PKIG. Each is linked with LAMTOR1 in more than 3 cancer types. Because this analysis shows association rather than direction, both LAMTOR1-to-partner and partner-to-LAMTOR1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LAMTOR1 versus C18orf54 in GBM, with a Pearson correlation of -0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LAMTOR1→partner) and Y-score (partner→LAMTOR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	C18orf54 →	-0.825	-0.210	<.001	<.001	3	4
COAD	TMEM41B →	+0.466	+0.190	<.001	<.001	3	3
HNSC	PKIG →	-0.707	-0.202	<.001	<.001	3	3
UCEC	MAGEH1 →	-1.049	-0.308	<.001	<.001	3	3
OV	LAYN →	-0.809	-0.219	.003	.005	3	3
HNSC	ANKRD36 →	-1.040	-0.287	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,301 associations by consensus.

LAMTOR1 vs C18orf54 — GBM

Explore this scatter interactively →