LAMP2

Across TCGA patient cohorts, LAMP2 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,581 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible LAMP2-associated proteins across cancer lineages are WDR44, G6PD, and PLS3. Each is linked with LAMP2 in more than 5 cancer types. Because this analysis shows association rather than direction, both LAMP2-to-partner and partner-to-LAMP2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LAMP2 versus WDR44 in OV, with a Pearson correlation of 0.46.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LAMP2→partner) and Y-score (partner→LAMP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	WDR44 →	+0.280	+0.531	<.001	.002	3	6
LSCC	G6PD →	+0.631	+0.449	<.001	<.001	3	5
COAD	PLS3 →	+0.443	+0.463	<.001	<.001	3	5
BRCA	CHAMP1 →	-0.275	-0.459	.003	.006	2	5
COAD	PGRMC1 →	+0.394	+0.527	<.001	<.001	3	4
BRCA	PSMD10 →	+0.242	+0.525	.002	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,581 associations by consensus.

LAMP2 vs WDR44 — OV

Explore this scatter interactively →