LAMP2

Across TCGA patient cohorts, LAMP2 protein abundance is significantly associated with the RNA expression of many other genes, with 10,551 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible LAMP2-associated genes across cancer lineages are SLC10A3, ZNF75D, and ZDHHC9. Each is linked with LAMP2 in more than 3 cancer types. Because this analysis shows association rather than direction, both LAMP2-to-partner and partner-to-LAMP2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LAMP2 versus SLC10A3 in LUAD, with a Pearson correlation of 0.37.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LAMP2→partner) and Y-score (partner→LAMP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	SLC10A3 →	+0.575	+0.517	<.001	<.001	3	4
OV	ZNF75D →	+0.705	+0.414	.001	.007	3	4
COAD	ZDHHC9 →	+0.793	+0.322	<.001	<.001	3	4
LUAD	MANBA →	+0.543	+0.565	<.001	<.001	3	4
OV	IL13RA1 →	+0.613	+0.358	<.001	.005	3	4
OV	WDR44 →	+0.653	+0.538	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,551 associations by consensus.

LAMP2 vs SLC10A3 — LUAD

Explore this scatter interactively →