Across TCGA patient cohorts, LAMP1 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,615 significant associations in total. GBM shows the largest number of these associations.

The most reproducible LAMP1-associated proteins across cancer lineages are CUL4A, TPP2, and TUBGCP3. Each is linked with LAMP1 in more than 6 cancer types. Because this analysis shows association rather than direction, both LAMP1-to-partner and partner-to-LAMP1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LAMP1→partner) and Y-score (partner→LAMP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	CUL4A →	+0.350	+0.677	<.001	<.001	3	7
BRCA	TPP2 →	+0.295	+0.485	<.001	<.001	3	6
OV	TUBGCP3 →	+0.249	+0.749	.001	<.001	3	4
BRCA	LIG4 →	+0.224	+0.486	.007	<.001	3	4
BRCA	STK24 →	+0.248	+0.455	<.001	<.001	2	4
LSCC	TMCO3 →	+0.827	+0.940	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,615 associations by consensus.

Exploration

LAMP1 survival (RNA) · tumor vs normal (RNA) · all LAMP1 data types