LAMC3

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, LAMC3 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,129 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible LAMC3-associated proteins across cancer lineages are MMRN2, NID1, and TNXB. Each is linked with LAMC3 in more than 5 cancer types. Because this analysis shows association rather than direction, both LAMC3-to-partner and partner-to-LAMC3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LAMC3 versus MMRN2 in CCRCC, with a Pearson correlation of 0.53.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LAMC3→partner) and Y-score (partner→LAMC3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CCRCCMMRN2 →+0.511+0.866<.001<.00136
GBMNID1 →+0.482+0.670<.001<.00136
CCRCCTNXB →+0.770+1.124<.001<.00135
GBMCOL18A1 →+0.717+0.954<.001<.00134
GBMERG_S81 →+0.680+0.686<.001.00334
CCRCCKANK3_S160 →+0.760+0.903<.001<.00134
Each partner links to its Q-omics profile. Showing the 6 strongest of 9,129 associations by consensus.

LAMC3 vs MMRN2 — CCRCC

Per-sample scatter of LAMC3 vs MMRN2 in CCRCC (Pearson r = 0.53).

Explore this scatter interactively →

Exploration