LAMC3

Across TCGA cell cohorts, LAMC3 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,088 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible LAMC3-associated GO terms across cancer lineages are Negative regulation of interferon-alpha production, tRNA transcription, and Heterochromatin organization. Each is linked with LAMC3 in more than 11 cancer types. Because this analysis shows association rather than direction, both LAMC3-to-partner and partner-to-LAMC3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of interferon-alpha production grouped by LAMC3-low versus LAMC3-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LAMC3→partner) and Y-score (partner→LAMC3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Negative regulation of interferon-alpha production →	+0.848	+1.093	<.001	<.001	3	12
OESOPHAGUS	tRNA transcription →	+0.102	+2.009	<.001	<.001	3	11
OVARY	Heterochromatin organization →	+0.063	+1.111	<.001	.002	3	9
OESOPHAGUS	Protein-RNA complex organization →	+0.075	+1.856	<.001	<.001	3	9
BREAST	rRNA transcription →	+0.071	+0.988	.004	.005	3	9
LUNG_SCLC	IMP salvage →	+0.179	+1.222	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,088 associations by consensus.

Negative regulation of interferon-alpha production by LAMC3 expression — OVARY

Explore this box plot interactively →