LAMC2

Across TCGA patient cohorts, LAMC2 protein abundance is significantly associated with the RNA expression of many other genes, with 9,716 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible LAMC2-associated genes across cancer lineages are AHNAK2, LAMB3, and GJB3. Each is linked with LAMC2 in more than 7 cancer types. Because this analysis shows association rather than direction, both LAMC2-to-partner and partner-to-LAMC2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LAMC2 versus AHNAK2 in UCEC, with a Pearson correlation of 0.45.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LAMC2→partner) and Y-score (partner→LAMC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	AHNAK2 →	+1.672	+0.888	<.001	<.001	3	8
BRCA	LAMB3 →	+2.089	+1.265	<.001	<.001	3	8
LUAD	GJB3 →	+1.115	+0.854	<.001	<.001	3	7
BRCA	S100A10 →	+0.982	+0.791	<.001	<.001	3	7
HNSC	CAV2 →	+0.982	+0.852	<.001	.001	3	6
UCEC	PLAUR →	+0.991	+0.652	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,716 associations by consensus.

LAMC2 vs AHNAK2 — UCEC

Explore this scatter interactively →