LAMC2

Across TCGA cell cohorts, LAMC2 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,147 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible LAMC2-associated GO terms across cancer lineages are Cell-substrate adhesion, Biological process involved in interaction with host, and Cell-matrix adhesion. Each is linked with LAMC2 in more than 14 cancer types. Because this analysis shows association rather than direction, both LAMC2-to-partner and partner-to-LAMC2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cell-substrate adhesion grouped by LAMC2-low versus LAMC2-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LAMC2→partner) and Y-score (partner→LAMC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Cell-substrate adhesion →	+0.155	+1.047	<.001	.004	3	15
LARGE_INTESTINE	Biological process involved in interaction with host →	+0.098	+2.603	<.001	<.001	3	14
OESOPHAGUS	Cell-matrix adhesion →	+0.138	+4.058	<.001	<.001	3	14
LUNG_NSCLC_LUAD	Rho protein signal transduction →	+0.130	+3.816	<.001	<.001	3	14
LIVER	Formation of primary germ layer →	+0.138	+3.931	.003	<.001	3	13
BONE	Viral life cycle →	+0.121	+0.963	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,147 associations by consensus.

Cell-substrate adhesion by LAMC2 expression — BONE

Explore this box plot interactively →