LAMB2

Across TCGA patient cohorts, LAMB2 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,220 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible LAMB2-associated proteins across cancer lineages are KANK2, GSN, and PARVA. Each is linked with LAMB2 in more than 7 cancer types. Because this analysis shows association rather than direction, both LAMB2-to-partner and partner-to-LAMB2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LAMB2 versus KANK2 in BRCA, with a Pearson correlation of 0.60.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LAMB2→partner) and Y-score (partner→LAMB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	KANK2 →	+0.514	+1.217	<.001	<.001	3	8
PDAC	GSN →	+0.803	+0.571	<.001	<.001	3	7
BRCA	PARVA →	+0.412	+0.755	<.001	<.001	3	6
BRCA	ARHGEF17_S735 →	+0.422	+0.771	<.001	<.001	3	6
CCRCC	RPL5 →	-0.230	-0.553	.001	.003	3	6
PDAC	SEPTIN8 →	+0.346	+0.501	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,220 associations by consensus.

LAMB2 vs KANK2 — BRCA

Explore this scatter interactively →