LAMB2

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, LAMB2 protein abundance is significantly associated with the RNA expression of many other genes, with 15,521 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible LAMB2-associated genes across cancer lineages are LINC01197, RASL12, and ASPA. Each is linked with LAMB2 in more than 8 cancer types. Because this analysis shows association rather than direction, both LAMB2-to-partner and partner-to-LAMB2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LAMB2 versus LINC01197 in CCRCC, with a Pearson correlation of 0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LAMB2→partner) and Y-score (partner→LAMB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CCRCCLINC01197 →+0.594+0.468<.001.00539
UCECRASL12 →+0.930+0.585<.001<.00138
CCRCCASPA →+1.146+0.393.002.00838
HNSCSGCA →+1.119+0.747<.001<.00138
CCRCCFHL5 →+1.386+0.541<.001<.00138
OVC7 →+2.864+0.476<.001<.00138
Each partner links to its Q-omics profile. Showing the 6 strongest of 15,521 associations by consensus.

LAMB2 vs LINC01197 — CCRCC

Per-sample scatter of LAMB2 vs LINC01197 in CCRCC (Pearson r = 0.40).

Explore this scatter interactively →

Exploration