LAMB1

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, LAMB1 protein abundance is significantly associated with the RNA expression of many other genes, with 16,271 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible LAMB1-associated genes across cancer lineages are FLT1, COL4A1, and ACTA2. Each is linked with LAMB1 in more than 9 cancer types. Because this analysis shows association rather than direction, both LAMB1-to-partner and partner-to-LAMB1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LAMB1 versus FLT1 in OV, with a Pearson correlation of 0.46.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LAMB1→partner) and Y-score (partner→LAMB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVFLT1 →+1.056+0.775<.001<.001310
OVCOL4A1 →+1.250+0.564<.001<.001310
OVACTA2 →+1.839+0.453<.001<.00139
OVLAMA4 →+1.150+0.478<.001<.00139
BRCACALD1 →+1.137+0.437<.001<.00139
OVCOL4A2 →+1.277+0.527<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 16,271 associations by consensus.

LAMB1 vs FLT1 — OV

Per-sample scatter of LAMB1 vs FLT1 in OV (Pearson r = 0.46).

Explore this scatter interactively →

Exploration