LAMA5

Across TCGA cell cohorts, LAMA5 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,737 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible LAMA5-associated GO terms across cancer lineages are Regulation of myoblast fusion, Negative regulation of RNA catabolic process, and Protein stabilization. Each is linked with LAMA5 in more than 12 cancer types. Because this analysis shows association rather than direction, both LAMA5-to-partner and partner-to-LAMA5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of myoblast fusion grouped by LAMA5-low versus LAMA5-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LAMA5→partner) and Y-score (partner→LAMA5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Regulation of myoblast fusion →	+0.112	+2.488	<.001	.004	3	13
OESOPHAGUS	Negative regulation of RNA catabolic process →	+0.078	+2.179	.001	.001	3	13
STOMACH	Protein stabilization →	+0.081	+2.570	<.001	.001	3	12
KIDNEY	Negative regulation of respiratory burst involved in inflammatory response →	+0.159	+3.246	.002	<.001	3	12
KIDNEY	Negative regulation of respiratory burst →	+0.159	+3.246	.002	<.001	3	12
OESOPHAGUS	Negative regulation of myoblast fusion →	+0.115	+1.830	.003	.002	2	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,737 associations by consensus.

Regulation of myoblast fusion by LAMA5 expression — KIDNEY

Explore this box plot interactively →