Across TCGA patient cohorts, LAMA2 protein abundance is significantly associated with the RNA expression of many other genes, with 12,731 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible LAMA2-associated genes across cancer lineages are CDO1, C7, and ABCA9. Each is linked with LAMA2 in more than 8 cancer types. Because this analysis shows association rather than direction, both LAMA2-to-partner and partner-to-LAMA2 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LAMA2→partner) and Y-score (partner→LAMA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CDO1 →	+1.476	+0.804	<.001	<.001	3	9
CCRCC	C7 →	+2.850	+0.969	<.001	<.001	3	8
BRCA	ABCA9 →	+1.030	+0.615	<.001	<.001	3	7
OV	PGM5 →	+1.236	+0.671	<.001	<.001	3	7
UCEC	CSDC2 →	+0.972	+0.830	<.001	<.001	3	7
BRCA	PABPC5 →	+0.795	+0.624	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,731 associations by consensus.

Exploration

LAMA2 survival (RNA) · tumor vs normal (RNA) · all LAMA2 data types