LAMA1

Across TCGA pan-cancer cohorts, LAMA1 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated LAMA1 data layer compared with 25 for mass-spec protein and 13 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher LAMA1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated LAMA1 expression acts as an unfavorable survival marker, although some lineages such as LSCC show a favorable association.

CCRCC, LSCC, and PDAC are the cancer types where LAMA1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Tertile	II,III,IV	0.173	0.985	.006	34	view →
LSCC	DFS	Median	All	0.992	0.872	.014	3	view →
PDAC	DFS	Quartile	II,III,IV	0.373	0.612	.041	2	view →
GBM	DFS	Median	All	0.202	0.318	.027	2	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

LAMA1–CCRCC (DFS)

Open the CCRCC breakdown →