LAIR1

Across TCGA patient cohorts, LAIR1 protein abundance is significantly associated with the RNA expression of many other genes, with 16,759 significant associations in total. GBM shows the largest number of these associations.

The most reproducible LAIR1-associated genes across cancer lineages are BIN2, DOCK2, and IFI30. Each is linked with LAIR1 in more than 9 cancer types. Because this analysis shows association rather than direction, both LAIR1-to-partner and partner-to-LAIR1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LAIR1 versus BIN2 in LSCC, with a Pearson correlation of 0.87.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LAIR1→partner) and Y-score (partner→LAIR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	BIN2 →	+1.062	+0.674	<.001	<.001	3	10
COAD	DOCK2 →	+1.275	+0.571	<.001	<.001	3	10
GBM	IFI30 →	+0.894	+0.820	<.001	<.001	3	10
COAD	SIRPB1 →	+0.821	+0.455	<.001	.003	3	9
COAD	CD4 →	+1.821	+0.571	<.001	<.001	3	9
GBM	IL10RA →	+1.297	+0.981	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,759 associations by consensus.

LAIR1 vs BIN2 — LSCC

Explore this scatter interactively →