LAIR1

Across TCGA cell cohorts, LAIR1 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,889 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible LAIR1-associated GO terms across cancer lineages are DNA damage response, signal transduction by p53 class mediator, HRI-mediated signaling, and Mitochondrial electron transport, cytochrome c to oxygen. Each is linked with LAIR1 in more than 7 cancer types. Because this analysis shows association rather than direction, both LAIR1-to-partner and partner-to-LAIR1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA damage response, signal transduction by p53 class mediator grouped by LAIR1-low versus LAIR1-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LAIR1→partner) and Y-score (partner→LAIR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	DNA damage response, signal transduction by p53 class mediator →	+0.057	+2.511	.003	.001	2	8
OESOPHAGUS	HRI-mediated signaling →	+0.071	+0.105	.006	<.001	2	8
LARGE_INTESTINE	Mitochondrial electron transport, cytochrome c to oxygen →	+0.062	+0.111	<.001	<.001	3	7
BLOOD_Lymphoma	Cellular response to glucose starvation →	+0.051	+2.913	<.001	<.001	3	6
OESOPHAGUS	Regulation of ubiquitin-dependent protein catabolic process →	+0.057	+0.087	<.001	.006	3	6
BLOOD_Leukemia	Neutrophil-mediated killing of fungus →	+1.052	+2.011	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,889 associations by consensus.

DNA damage response, signal transduction by p53 class mediator by LAIR1 expression — BLOOD_Lymphoma

Explore this box plot interactively →