L antigen family member 3 pseudogene 1Genealiases: []
Q-omics provides the consensus-scored LAGE3P1 profile across patient tissues and cancer cell-line models. LAGE3P1 expression is associated with patient survival in 21 of 34 cancer types, with the highest sampling consensus in LIHC. Among the 18 cancer types available for tumor–normal comparison, LAGE3P1 is differentially expressed in 11, with the highest sampling consensus in COAD. Additionally, LAGE3P1 RNA expression shows 14,896 significant gene co-expression associations, with the highest sampling consensus in UVM. Together, these results highlight LIHC, COAD, and UVM as cancer lineages where LAGE3P1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for LAGE3P1 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes LAGE3P1 survival associations across molecular data types. LAGE3P1 RNA expression shows survival associations in the most cancer types (21). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible LAGE3P1 RNA expression–survival associations across cancer types. High LAGE3P1 expression shows unfavorable associations in LIHC, ACC and KIRC, but favorable associations in THYM, OV and LGG. The LIHC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify LIHC as the clearest survival context for LAGE3P1 RNA expression.
This table summarizes LAGE3P1 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 11. The strongest signals are observed in HNSC for RNA.
This table ranks reproducible tumor–normal expression differences for LAGE3P1. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. LAGE3P1 shows higher tumor expression in COAD, HNSC, LIHC, READ, BLCA and LUSC. The COAD box plot shows higher LAGE3P1 RNA expression in tumor versus normal tissue (log2 FC = +0.687, t-test p < 0.001).
This table shows molecular features associated with LAGE3P1 in patient tissues and cancer cell lines. In patient samples, LAGE3P1 shows the broadest associations at the RNA and protein expression levels, with UVM recurring as the lineage with the largest associated feature set.
