LAG3

Across TCGA patient cohorts, LAG3 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,217 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible LAG3-associated proteins across cancer lineages are TYMP, STAT1, and LCP2. Each is linked with LAG3 in more than 9 cancer types. Because this analysis shows association rather than direction, both LAG3-to-partner and partner-to-LAG3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LAG3 versus TYMP in OV, with a Pearson correlation of 0.45.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LAG3→partner) and Y-score (partner→LAG3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	TYMP →	+0.725	+0.969	<.001	<.001	3	10
LSCC	STAT1 →	+0.754	+0.899	<.001	<.001	3	10
HNSC	LCP2 →	+0.548	+1.152	<.001	<.001	3	10
COAD	WARS1 →	+0.858	+1.075	<.001	<.001	3	9
UCEC	PLEK →	+0.808	+1.013	<.001	<.001	3	9
OV	RASAL3 →	+0.546	+0.767	<.001	.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,217 associations by consensus.

LAG3 vs TYMP — OV

Explore this scatter interactively →