Across TCGA cell cohorts, LACTBL1 mutation is significantly associated with the RNA expression of many other genes, with 11 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible LACTBL1-associated genes across cancer lineages are SLC32A1, ATXN3L, and BHLHE23. Each is linked with LACTBL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both LACTBL1-to-partner and partner-to-LACTBL1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LACTBL1→partner) and Y-score (partner→LACTBL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	SLC32A1 →	+0.017	+3.672	<.001	.006	3	1
BREAST	ATXN3L →	+0.369	+4.415	.001	.001	3	1
BREAST	BHLHE23 →	+0.090	+4.196	<.001	.006	3	1
BREAST	MRGPRE →	+0.542	+3.758	<.001	.007	3	1
BREAST	C5orf52 →	+0.036	+4.196	<.001	.006	3	1
BREAST	OR13C5 →	+0.023	+4.312	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

Exploration

LACTBL1 survival (RNA) · tumor vs normal (RNA) · all LACTBL1 data types