LACTB2

Across TCGA cell cohorts, LACTB2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,577 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible LACTB2-associated GO terms across cancer lineages are Synaptic vesicle lumen acidification, Endosome organization, and Anterograde dendritic transport of messenger ribonucleoprotein complex. Each is linked with LACTB2 in more than 9 cancer types. Because this analysis shows association rather than direction, both LACTB2-to-partner and partner-to-LACTB2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Synaptic vesicle lumen acidification grouped by LACTB2-low versus LACTB2-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LACTB2→partner) and Y-score (partner→LACTB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Synaptic vesicle lumen acidification →	+0.137	+0.929	<.001	<.001	3	10
LIVER	Endosome organization →	+0.081	+1.130	<.001	<.001	3	8
SOFT_TISSUE	Anterograde dendritic transport of messenger ribonucleoprotein complex →	+0.165	+0.681	.002	.009	3	8
SOFT_TISSUE	Fatty acid metabolic process →	+0.050	+0.688	.003	.007	3	8
BONE	Synaptic vesicle maturation →	+0.129	+0.863	.001	<.001	3	8
LUNG_SCLC	Lipid catabolic process →	+0.041	+0.994	.004	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,577 associations by consensus.

Synaptic vesicle lumen acidification by LACTB2 expression — BONE

Explore this box plot interactively →