LACRT

Across TCGA patient cohorts, LACRT RNA expression is significantly associated with the go_rna of many other GO terms, with 5,946 significant associations in total. STAD shows the largest number of these associations.

The most reproducible LACRT-associated GO terms across cancer lineages are Branching morphogenesis of an epithelial tube, Developmental cell growth, and Regulation of protein secretion. Each is linked with LACRT in more than 6 cancer types. Because this analysis shows association rather than direction, both LACRT-to-partner and partner-to-LACRT results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Branching morphogenesis of an epithelial tube grouped by LACRT-low versus LACRT-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LACRT→partner) and Y-score (partner→LACRT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Branching morphogenesis of an epithelial tube →	+0.067	+0.051	<.001	<.001	3	6
STAD	Developmental cell growth →	+0.062	+0.090	<.001	<.001	3	5
STAD	Regulation of protein secretion →	+0.065	+0.096	<.001	<.001	3	5
STAD	Regulation of insulin secretion →	+0.058	+0.054	<.001	<.001	3	5
STAD	Neural precursor cell proliferation →	+0.056	+0.053	<.001	<.001	3	5
STAD	Positive regulation of protein serine/threonine kinase activity →	+0.072	+0.094	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,946 associations by consensus.

Branching morphogenesis of an epithelial tube by LACRT expression — STAD

Explore this box plot interactively →