LACC1

Across TCGA pan-cancer cohorts, LACC1 Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated LACC1 data layer compared with 26 for mass-spec protein and 3 for mass-spec protein.

The strongest signal is observed in ovarian serous cystadenocarcinoma (OV), where higher LACC1 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated LACC1 expression acts as an unfavorable survival marker.

OV, CESC, and SKCM are the cancer types where LACC1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
OV	OS	Median	II,III,IV	0.278	0.843	<.001	36	view →
CESC	OS	Median	II,III,IV	0.068	0.830	<.001	30	view →
SKCM	OS	Median	IV	0.179	0.727	<.001	6	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

LACC1–OV (OS)

Open the OV breakdown →