LACC1

Across TCGA patient cohorts, LACC1 RNA expression is significantly associated with the RNA expression of many other genes, with 19,111 significant associations in total. UVM shows the largest number of these associations.

The most reproducible LACC1-associated genes across cancer lineages are ZDHHC20, NHLRC3, and PARP4. Each is linked with LACC1 in more than 32 cancer types. Because this analysis shows association rather than direction, both LACC1-to-partner and partner-to-LACC1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LACC1 versus ZDHHC20 in UVM, with a Pearson correlation of 0.85.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LACC1→partner) and Y-score (partner→LACC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UVM	ZDHHC20 →	+1.625	+1.254	<.001	<.001	3	33
UVM	NHLRC3 →	+1.311	+1.155	<.001	<.001	3	33
UVM	PARP4 →	+1.461	+1.192	<.001	<.001	3	33
KICH	LIPA →	+1.353	+0.918	<.001	<.001	3	33
UVM	MOB1A →	+1.428	+1.207	<.001	<.001	3	33
UVM	UFM1 →	+1.483	+1.220	<.001	<.001	3	33

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,111 associations by consensus.

LACC1 vs ZDHHC20 — UVM

Explore this scatter interactively →