LACC1

Across TCGA patient cohorts, LACC1 protein abundance is significantly associated with the RNA expression of many other genes, with 10,136 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible LACC1-associated genes across cancer lineages are CYTH4, IL21R, and LILRB1. Each is linked with LACC1 in more than 6 cancer types. Because this analysis shows association rather than direction, both LACC1-to-partner and partner-to-LACC1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LACC1 versus CYTH4 in UCEC, with a Pearson correlation of 0.45.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LACC1→partner) and Y-score (partner→LACC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CYTH4 →	+0.732	+0.317	<.001	<.001	3	7
LUAD	IL21R →	+0.900	+0.288	<.001	<.001	3	7
UCEC	LILRB1 →	+1.266	+0.556	<.001	<.001	3	7
UCEC	CD4 →	+0.919	+0.415	<.001	<.001	3	7
BRCA	SLC15A3 →	+1.015	+0.405	<.001	<.001	3	7
UCEC	TYROBP →	+1.384	+0.532	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,136 associations by consensus.

LACC1 vs CYTH4 — UCEC

Explore this scatter interactively →