LACC1

Across TCGA cell cohorts, LACC1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,088 significant associations in total. BONE shows the largest number of these associations.

The most reproducible LACC1-associated GO terms across cancer lineages are Multivesicular body organization, Multivesicular body assembly, and Regulation of plasma membrane organization. Each is linked with LACC1 in more than 13 cancer types. Because this analysis shows association rather than direction, both LACC1-to-partner and partner-to-LACC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Multivesicular body organization grouped by LACC1-low versus LACC1-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LACC1→partner) and Y-score (partner→LACC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Multivesicular body organization →	+0.118	+1.031	<.001	<.001	3	14
PANCREAS	Multivesicular body assembly →	+0.117	+1.128	<.001	<.001	3	12
LIVER	Regulation of plasma membrane organization →	+0.190	+1.020	.001	.006	3	11
BONE	Ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway →	+0.085	+1.270	<.001	.003	3	11
BONE	Cellular response to mechanical stimulus →	+0.097	+1.728	<.001	<.001	3	11
BONE	Positive regulation of translational initiation in response to stress →	+0.154	+1.378	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,088 associations by consensus.

Multivesicular body organization by LACC1 expression — PANCREAS

Explore this box plot interactively →