LACC1

Across TCGA cell cohorts, LACC1 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. CNS shows the largest number of these associations.

The most reproducible LACC1-associated genes across cancer lineages are PRM3 and RXFP3. Each is linked with LACC1 in more than 1 cancer types. Because this analysis shows association rather than direction, both LACC1-to-partner and partner-to-LACC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PRM3 grouped by LACC1-low versus LACC1-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LACC1→partner) and Y-score (partner→LACC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	PRM3 →	+0.133	+4.754	<.001	.005	3	1
CNS	RXFP3 →	+0.063	+4.169	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

PRM3 by LACC1 expression — CNS

Explore this box plot interactively →